Impact of obesity on immune function and depressive disorder: integrative review

Objective: This integrative review aims to search and analyze scientific evidence on the relationship between obesity, immune function, depressive disorder. Methods: The present study is a descriptive of literature concerning keywords: depression, immunologic, inflammation, psychoneuroimmunology cytokines. inclusion criteria were: articles published in english; referring indexed PubMed database last 17 years. Results: A large amount indicates that function seems be compromised obesity has, through this, trigger symptom. However, more still needed better elucidate pathophysiology components incidences associated immunological alterations. Conclusions: pathophysiological scenario closely related changes these may promote symptoms various physiological mechanisms thus negatively impact mental health status.